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S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination

Immunoglobulin class switch recombination is governed by long-range interactions between enhancers and germline transcript promoters to activate transcription and modulate chromatin accessibility to activation-induced cytidine deaminase (AID). However, mechanisms leading to the differential targetin...

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Detalles Bibliográficos
Autores principales: Wang, Lili, Wuerffel, Robert, Feldman, Scott, Khamlichi, Ahmed Amine, Kenter, Amy L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722165/
https://www.ncbi.nlm.nih.gov/pubmed/19596805
http://dx.doi.org/10.1084/jem.20081678