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Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease

Activin-A is a pleiotropic cytokine that participates in developmental, inflammatory, and tissue repair processes. Still, its effects on T helper (Th) cell–mediated immunity, critical for allergic and autoimmune diseases, are elusive. We provide evidence that endogenously produced activin-A suppress...

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Detalles Bibliográficos
Autores principales: Semitekolou, Maria, Alissafi, Themis, Aggelakopoulou, Maria, Kourepini, Evangelia, Kariyawasam, Harsha H., Kay, Antony B., Robinson, Douglas S., Lloyd, Clare M., Panoutsakopoulou, Vily, Xanthou, Georgina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722168/
https://www.ncbi.nlm.nih.gov/pubmed/19620629
http://dx.doi.org/10.1084/jem.20082603