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Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease
Activin-A is a pleiotropic cytokine that participates in developmental, inflammatory, and tissue repair processes. Still, its effects on T helper (Th) cell–mediated immunity, critical for allergic and autoimmune diseases, are elusive. We provide evidence that endogenously produced activin-A suppress...
Autores principales: | Semitekolou, Maria, Alissafi, Themis, Aggelakopoulou, Maria, Kourepini, Evangelia, Kariyawasam, Harsha H., Kay, Antony B., Robinson, Douglas S., Lloyd, Clare M., Panoutsakopoulou, Vily, Xanthou, Georgina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722168/ https://www.ncbi.nlm.nih.gov/pubmed/19620629 http://dx.doi.org/10.1084/jem.20082603 |
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