NF-κB activity marks cells engaged in receptor editing

Because of the extreme diversity in immunoglobulin genes, tolerance mechanisms are necessary to ensure that B cells do not respond to self-antigens. One such tolerance mechanism is called receptor editing. If the B cell receptor (BCR) on an immature B cell recognizes self-antigen, it is down-regulat...

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Detalles Bibliográficos
Autores principales: Cadera, Emily J., Wan, Fengyi, Amin, Rupesh H., Nolla, Hector, Lenardo, Michael J., Schlissel, Mark S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722169/
https://www.ncbi.nlm.nih.gov/pubmed/19581408
http://dx.doi.org/10.1084/jem.20082815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722169/
https://www.ncbi.nlm.nih.gov/pubmed/19581408
http://dx.doi.org/10.1084/jem.20082815

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