Hepatocyte-specific NEMO deletion promotes NK/NKT cell– and TRAIL-dependent liver damage

Nuclear factor κB (NF-κB) is one of the main transcription factors involved in regulating apoptosis, inflammation, chronic liver disease, and cancer progression. The IKK complex mediates NF-κB activation and deletion of its regulatory subunit NEMO in hepatocytes (NEMO(Δhepa)) triggers chronic inflam...

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Detalles Bibliográficos
Autores principales: Beraza, Naiara, Malato, Yann, Sander, Leif E., Al-Masaoudi, Malika, Freimuth, Julia, Riethmacher, Dieter, Gores, Gregory J., Roskams, Tania, Liedtke, Christian, Trautwein, Christian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722179/
https://www.ncbi.nlm.nih.gov/pubmed/19635861
http://dx.doi.org/10.1084/jem.20082152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722179/
https://www.ncbi.nlm.nih.gov/pubmed/19635861
http://dx.doi.org/10.1084/jem.20082152

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