F-Box Protein FBXO31 Mediates Cyclin D1 Degradation to Induce G1 Arrest Following DNA Damage

In response to DNA damage eukaryotic cells initiate a complex signalling pathway, termed the DNA damage response (DDR), which coordinates cell cycle arrest with DNA repair. Studies have shown that oncogene-induced senescence, which provides a barrier to tumour development, involves activation of the...

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Detalles Bibliográficos
Autores principales: Santra, Manas K., Wajapeyee, Narendra, Green, Michael R.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722223/
https://www.ncbi.nlm.nih.gov/pubmed/19412162
http://dx.doi.org/10.1038/nature08011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722223/
https://www.ncbi.nlm.nih.gov/pubmed/19412162
http://dx.doi.org/10.1038/nature08011

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