Taming the tiger by the tail: modulation of DNA damage responses by telomeres

Telomeres are by definition stable and inert chromosome ends, whereas internal chromosome breaks are potent stimulators of the DNA damage response (DDR). Telomeres do not, as might be expected, exclude DDR proteins from chromosome ends but instead engage with many DDR proteins. However, the most pow...

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Detalles Bibliográficos
Autor principal: Lydall, David
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722249/
https://www.ncbi.nlm.nih.gov/pubmed/19629039
http://dx.doi.org/10.1038/emboj.2009.176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722249/
https://www.ncbi.nlm.nih.gov/pubmed/19629039
http://dx.doi.org/10.1038/emboj.2009.176

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