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Taming the tiger by the tail: modulation of DNA damage responses by telomeres
Telomeres are by definition stable and inert chromosome ends, whereas internal chromosome breaks are potent stimulators of the DNA damage response (DDR). Telomeres do not, as might be expected, exclude DDR proteins from chromosome ends but instead engage with many DDR proteins. However, the most pow...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722249/ https://www.ncbi.nlm.nih.gov/pubmed/19629039 http://dx.doi.org/10.1038/emboj.2009.176 |