Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase

The conventional DNA polymerase machinery is unable to fully replicate the ends of linear chromosomes. To surmount this problem, nearly all eukaryotes use the telomerase enzyme, a specialized reverse transcriptase that utizes its own RNA template to add short TG-rich repeats to chromosome ends, thus...

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Detalles Bibliográficos
Autores principales: Shore, David, Bianchi, Alessandro
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Focus Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722252/
https://www.ncbi.nlm.nih.gov/pubmed/19629031
http://dx.doi.org/10.1038/emboj.2009.195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722252/
https://www.ncbi.nlm.nih.gov/pubmed/19629031
http://dx.doi.org/10.1038/emboj.2009.195

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