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Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases

Asparagine-linked glycosylation is catalysed by oligosaccharyltransferase (OTase). In Trypanosoma brucei OTase activity is catalysed by single-subunit enzymes encoded by three paralogous genes of which TbSTT3B and TbSTT3C can complement a yeast Δstt3 mutant. The two enzymes have overlapping but dist...

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Detalles Bibliográficos
Autores principales: Izquierdo, Luis, Schulz, Benjamin L, Rodrigues, João A, Güther, Maria Lucia S, Procter, James B, Barton, Geoffrey J, Aebi, Markus, Ferguson, Michael A J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722254/
https://www.ncbi.nlm.nih.gov/pubmed/19629045
http://dx.doi.org/10.1038/emboj.2009.203