Cargando…
Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
The intraerythrocytic parasite Plasmodium—the causative agent of malaria—produces an inorganic crystal called hemozoin (Hz) during the heme detoxification process, which is released into the circulation during erythrocyte lysis. Hz is rapidly ingested by phagocytes and induces the production of seve...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722371/ https://www.ncbi.nlm.nih.gov/pubmed/19696895 http://dx.doi.org/10.1371/journal.ppat.1000559 |