Hes1 Potentiates T Cell Lymphomagenesis by Up-Regulating a Subset of Notch Target Genes

BACKGROUND: Hairy/Enhancer of Split (Hes) proteins are targets of the Notch signaling pathway and make up a class of basic helix-loop-helix (bHLH) proteins that function to repress transcription. Data from Hes1 deficient mice suggested that Hes1, like Notch1, is necessary for the progression of earl...

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Detalles Bibliográficos
Autores principales: Dudley, Darryll D., Wang, Hong-Cheng, Sun, Xiao-Hong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722736/
https://www.ncbi.nlm.nih.gov/pubmed/19688092
http://dx.doi.org/10.1371/journal.pone.0006678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722736/
https://www.ncbi.nlm.nih.gov/pubmed/19688092
http://dx.doi.org/10.1371/journal.pone.0006678

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