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Hes1 Potentiates T Cell Lymphomagenesis by Up-Regulating a Subset of Notch Target Genes
BACKGROUND: Hairy/Enhancer of Split (Hes) proteins are targets of the Notch signaling pathway and make up a class of basic helix-loop-helix (bHLH) proteins that function to repress transcription. Data from Hes1 deficient mice suggested that Hes1, like Notch1, is necessary for the progression of earl...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722736/ https://www.ncbi.nlm.nih.gov/pubmed/19688092 http://dx.doi.org/10.1371/journal.pone.0006678 |