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N2′→P3′ Phosphoramidate Glycerol Nucleic Acid as a Potential Alternative Genetic System
[Image: see text] Glycerol nucleic acid (GNA) is an interesting base-pairing system with an acyclic, three-carbon backbone. In the present study, GNA analogues with N2′→P3′ phosphoramidate linkages (npGNA) have been synthesized and their base-pairing properties examined. Thermal denaturation and cir...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722806/ https://www.ncbi.nlm.nih.gov/pubmed/19166350 http://dx.doi.org/10.1021/ja809069b |