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N2′→P3′ Phosphoramidate Glycerol Nucleic Acid as a Potential Alternative Genetic System

[Image: see text] Glycerol nucleic acid (GNA) is an interesting base-pairing system with an acyclic, three-carbon backbone. In the present study, GNA analogues with N2′→P3′ phosphoramidate linkages (npGNA) have been synthesized and their base-pairing properties examined. Thermal denaturation and cir...

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Detalles Bibliográficos
Autores principales:	Chen, Jesse J., Cai, Xin, Szostak, Jack W.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2009
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722806/ https://www.ncbi.nlm.nih.gov/pubmed/19166350 http://dx.doi.org/10.1021/ja809069b

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