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Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

Co-amplification at chromosomes 8p11-8p12 and 11q12-11q14 occurs often in breast tumors, suggesting possible cooperation between genes in these regions in oncogenesis. We used high resolution array comparative genomic hybridization (array CGH) to map the minimal amplified regions. The 8p and 11q amp...

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Detalles Bibliográficos
Autores principales: Kwek, Serena S., Roy, Ritu, Zhou, Hua, Climent, Joan, Martinez-Climent, Jose A., Fridlyand, Jane, Albertson, Donna G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722962/
https://www.ncbi.nlm.nih.gov/pubmed/19330026
http://dx.doi.org/10.1038/onc.2009.34