Functional interaction of mammalian target of rapamycin complexes in regulating mammalian cell size and cell cycle

Dysregulation of the mammalian target of rapamycin (mTOR) kinase pathway is centrally involved in a wide variety of cancers and human genetic diseases. In mammalian cells, mTOR is part of two different kinase complexes: mTORC1 composed of mTOR, raptor and mLST8, and mTORC2 containing mTOR, rictor, s...

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Detalles Bibliográficos
Autores principales: Rosner, Margit, Fuchs, Christiane, Siegel, Nicol, Valli, Alessandro, Hengstschläger, Markus
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722991/
https://www.ncbi.nlm.nih.gov/pubmed/19505958
http://dx.doi.org/10.1093/hmg/ddp271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722991/
https://www.ncbi.nlm.nih.gov/pubmed/19505958
http://dx.doi.org/10.1093/hmg/ddp271

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