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Statistical detection of cooperative transcription factors with similarity adjustment

Motivation: Statistical assessment of cis-regulatory modules (CRMs) is a crucial task in computational biology. Usually, one concludes from exceptional co-occurrences of DNA motifs that the corresponding transcription factors (TFs) are cooperative. However, similar DNA motifs tend to co-occur in ran...

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Detalles Bibliográficos
Autores principales: Pape, Utz J., Klein, Holger, Vingron, Martin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722994/
https://www.ncbi.nlm.nih.gov/pubmed/19286833
http://dx.doi.org/10.1093/bioinformatics/btp143