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The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains
BACKGROUND: Brain tissue from patients with Alzheimer's disease has shown an increase of phosphorylation of Tyr-682, located on the conserved Y682ENPTY motif, and Thr-668 residues, both in the intracellular domain (AID) of amyloid β precursor protein (APP), although the role of these two residu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723102/ https://www.ncbi.nlm.nih.gov/pubmed/19602287 http://dx.doi.org/10.1186/1750-1326-4-28 |