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Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma

BACKGROUND: Renal cell carcinoma patients respond poorly to conventional chemotherapy, this unresponsiveness may be attributable to multidrug resistance (MDR). The mechanisms of MDR in renal cancer are not fully understood and the specific contribution of ABC transporter proteins which have been imp...

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Detalles Bibliográficos
Autores principales: Walsh, Naomi, Larkin, Annemarie, Kennedy, Susan, Connolly, Lisa, Ballot, Jo, Ooi, Wei, Gullo, Giuseppe, Crown, John, Clynes, Martin, O'Driscoll, Lorraine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723136/
https://www.ncbi.nlm.nih.gov/pubmed/19552816
http://dx.doi.org/10.1186/1471-2490-9-6