Cargando…

Delivery to the lower respiratory tract is required for effective immunization with Newcastle disease virus-vectored vaccines intended for humans

Newcastle disease virus (NDV), an avian virus, is being evaluated for the development of vectored human vaccines against emerging pathogens. Previous studies of NDV-vectored vaccines in a mouse model suggested their potency after delivery by injection or by the intranasal route. We compared the effi...

Descripción completa

Detalles Bibliográficos
Autores principales: DiNapoli, Joshua M., Ward, Jerrold M., Cheng, Lily, Yang, Lijuan, Elankumaran, Subbiah, Murphy, Brian R., Samal, Siba K., Collins, Peter L., Bukreyev, Alexander
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723768/
https://www.ncbi.nlm.nih.gov/pubmed/19168110
http://dx.doi.org/10.1016/j.vaccine.2009.01.009