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Delivery to the lower respiratory tract is required for effective immunization with Newcastle disease virus-vectored vaccines intended for humans
Newcastle disease virus (NDV), an avian virus, is being evaluated for the development of vectored human vaccines against emerging pathogens. Previous studies of NDV-vectored vaccines in a mouse model suggested their potency after delivery by injection or by the intranasal route. We compared the effi...
Autores principales: | DiNapoli, Joshua M., Ward, Jerrold M., Cheng, Lily, Yang, Lijuan, Elankumaran, Subbiah, Murphy, Brian R., Samal, Siba K., Collins, Peter L., Bukreyev, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723768/ https://www.ncbi.nlm.nih.gov/pubmed/19168110 http://dx.doi.org/10.1016/j.vaccine.2009.01.009 |
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