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Many X-linked microRNAs escape meiotic sex chromosome inactivation

Meiotic sex chromosome inactivation (MSCI) during spermatogenesis is characterized by transcriptional silencing of genes on both the X and Y chromosomes in mid to late pachytene spermatocytes1. MSCI is believed to result from meiotic silencing of unpaired DNA because the X and Y chromosomes remain l...

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Detalles Bibliográficos
Autores principales: Song, Rui, Ro, Seungil, Michaels, Jason D., Park, Chanjae, McCarrey, John R., Yan, Wei
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723799/
https://www.ncbi.nlm.nih.gov/pubmed/19305411
http://dx.doi.org/10.1038/ng.338