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Multiple var2csa-Type PfEMP1 Genes Located at Different Chromosomal Loci Occur in Many Plasmodium falciparum Isolates

BACKGROUND: The var2csa gene encodes a Plasmodium falciparum adhesion receptor which binds chondroitin sulfate A (CSA). This var gene is more conserved than other PfEMP1/var genes and is found in all P. falciparum isolates. In isolates 3D7, FCR3/It4 and HB3, var2csa is transcribed from a sub-telomer...

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Detalles Bibliográficos
Autores principales: Sander, Adam F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten A., Magistrado, Pamela, Lusingu, John, Ndam, Nicaise Tuikue, Arnot, David E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723927/
https://www.ncbi.nlm.nih.gov/pubmed/19690615
http://dx.doi.org/10.1371/journal.pone.0006667