Transgene Expression Is Associated with Copy Number and Cytomegalovirus Promoter Methylation in Transgenic Pigs

Transgenic animals have been used for years to study gene function, produce important proteins, and generate models for the study of human diseases. However, inheritance and expression instability of the transgene in transgenic animals is a major limitation. Copy number and promoter methylation are...

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Detalles Bibliográficos
Autores principales: Kong, Qingran, Wu, Meiling, Huan, Yanjun, Zhang, Li, Liu, Haiyan, Bou, Gerelchimeg, Luo, Yibo, Mu, Yanshuang, Liu, Zhonghua
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723931/
https://www.ncbi.nlm.nih.gov/pubmed/19688097
http://dx.doi.org/10.1371/journal.pone.0006679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723931/
https://www.ncbi.nlm.nih.gov/pubmed/19688097
http://dx.doi.org/10.1371/journal.pone.0006679

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