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Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts

Cardiac myofibroblasts are pivotal to adaptive remodelling after myocardial infarction (MI). These normally quiescent cells invade and proliferate as a wound healing response, facilitated by activation of matrix metalloproteinases, particularly MMP-2. Following MI these reparative events occur under...

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Detalles Bibliográficos
Autores principales: Riches, Kirsten, Morley, Michael E., Turner, Neil A., O'Regan, David J., Ball, Stephen G., Peers, Chris, Porter, Karen E.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723933/
https://www.ncbi.nlm.nih.gov/pubmed/19523958
http://dx.doi.org/10.1016/j.yjmcc.2009.06.002