Down syndrome suppression of tumor growth and the role of the calcineurin inhibitor DSCR1

The incidence of many cancer types is significantly reduced in individuals with Down syndrome1–4 and it is proposed that this broad cancer protection is conferred by the elevated expression of one or more of the 231 supernumerary genes on the extra copy of chromosome 21. One such gene is the Down sy...

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Detalles Bibliográficos
Autores principales: Baek, Kwan-Hyuck, Zaslavsky, Alexander, Lynch, Ryan C., Britt, Carmella, Okada, Yoshiaki, Siarey, Richard J., Lensch, M. William, Park, In-Hyun, Yoon, Sam S., Minami, Takashi, Reeves, Roger, Korenberg, Julie R., Folkman, Judah, Daley, George Q., Aird, William C., Galdzicki, Zygmunt, Ryeom, Sandra
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724004/
https://www.ncbi.nlm.nih.gov/pubmed/19458618
http://dx.doi.org/10.1038/nature08062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724004/
https://www.ncbi.nlm.nih.gov/pubmed/19458618
http://dx.doi.org/10.1038/nature08062

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