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Down syndrome suppression of tumor growth and the role of the calcineurin inhibitor DSCR1
The incidence of many cancer types is significantly reduced in individuals with Down syndrome1–4 and it is proposed that this broad cancer protection is conferred by the elevated expression of one or more of the 231 supernumerary genes on the extra copy of chromosome 21. One such gene is the Down sy...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724004/ https://www.ncbi.nlm.nih.gov/pubmed/19458618 http://dx.doi.org/10.1038/nature08062 |