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The Salmonella Effector SptP Dephosphorylates Host AAA+ ATPase VCP to Promote Development of its Intracellular Replicative Niche

Virulence effectors delivered into intestinal epithelial cells by Salmonella trigger actin remodeling to direct pathogen internalization and intracellular replication in Salmonella-containing vacuoles (SCVs). One such effector, SptP, functions early during pathogen entry to deactivate Rho GTPases an...

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Detalles Bibliográficos
Autores principales: Humphreys, Daniel, Hume, Peter J., Koronakis, Vassilis
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724103/
https://www.ncbi.nlm.nih.gov/pubmed/19286132
http://dx.doi.org/10.1016/j.chom.2009.01.010