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Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC–MS/MS and evaluation of their stability in mice tissues

S-Adenosylmethionine (SAM) serves as a methyl donor in biological transmethylation reactions. S-Adenosylhomocysteine (SAH) is the product as well as the inhibitor of transmethylations and the ratio SAM/SAH is regarded as the measure of methylating capacity (“methylation index”). We present a rapid a...

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Detalles Bibliográficos
Autores principales: Krijt, Jakub, Dutá, Alena, Kožich, Viktor
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724122/
https://www.ncbi.nlm.nih.gov/pubmed/19502114
http://dx.doi.org/10.1016/j.jchromb.2009.05.039