Cargando…

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia

The transcription factor Hypoxia-inducible factor 1 (HIF-1) plays a central role in the transcriptional response to oxygen flux. To gain insight into the molecular pathways regulated by HIF-1, it is essential to identify the downstream-target genes. We report here a strategy to identify HIF-1-target...

Descripción completa

Detalles Bibliográficos
Autores principales: Benita, Yair, Kikuchi, Hirotoshi, Smith, Andrew D., Zhang, Michael Q., Chung, Daniel C., Xavier, Ramnik J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724271/
https://www.ncbi.nlm.nih.gov/pubmed/19491311
http://dx.doi.org/10.1093/nar/gkp425