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Using DNA mechanics to predict in vitro nucleosome positions and formation energies

In eukaryotic genomes, nucleosomes function to compact DNA and to regulate access to it both by simple physical occlusion and by providing the substrate for numerous covalent epigenetic tags. While competition with other DNA-binding factors and action of chromatin remodeling enzymes significantly af...

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Detalles Bibliográficos
Autores principales: Morozov, Alexandre V., Fortney, Karissa, Gaykalova, Daria A., Studitsky, Vasily M., Widom, Jonathan, Siggia, Eric D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724288/
https://www.ncbi.nlm.nih.gov/pubmed/19509309
http://dx.doi.org/10.1093/nar/gkp475