Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch

Riboswitches are a novel class of genetic control elements that function through the direct interaction of small metabolite molecules with structured RNA elements. The ligand is bound with high specificity and affinity to its RNA target and induces conformational changes of the RNA's secondary...

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Detalles Bibliográficos
Autores principales: Villa, Alessandra, Wöhnert, Jens, Stock, Gerhard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724292/
https://www.ncbi.nlm.nih.gov/pubmed/19515936
http://dx.doi.org/10.1093/nar/gkp486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724292/
https://www.ncbi.nlm.nih.gov/pubmed/19515936
http://dx.doi.org/10.1093/nar/gkp486

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