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Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch
Riboswitches are a novel class of genetic control elements that function through the direct interaction of small metabolite molecules with structured RNA elements. The ligand is bound with high specificity and affinity to its RNA target and induces conformational changes of the RNA's secondary...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724292/ https://www.ncbi.nlm.nih.gov/pubmed/19515936 http://dx.doi.org/10.1093/nar/gkp486 |