Efficient generation of long-distance conditional alleles using recombineering and a dual selection strategy in replicate plates

BACKGROUND: Conditional knockout mice are a useful tool to study the function of gene products in a tissue-specific or inducible manner. Classical approaches to generate targeting vectors for conditional alleles are often limited by the availability of suitable restriction sites. Furthermore, plasmi...

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Detalles Bibliográficos
Autores principales: Voehringer, David, Wu, Davina, Liang, Hong-Erh, Locksley, Richard M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724507/
https://www.ncbi.nlm.nih.gov/pubmed/19638212
http://dx.doi.org/10.1186/1472-6750-9-69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724507/
https://www.ncbi.nlm.nih.gov/pubmed/19638212
http://dx.doi.org/10.1186/1472-6750-9-69

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