Cargando…
Efficient generation of long-distance conditional alleles using recombineering and a dual selection strategy in replicate plates
BACKGROUND: Conditional knockout mice are a useful tool to study the function of gene products in a tissue-specific or inducible manner. Classical approaches to generate targeting vectors for conditional alleles are often limited by the availability of suitable restriction sites. Furthermore, plasmi...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724507/ https://www.ncbi.nlm.nih.gov/pubmed/19638212 http://dx.doi.org/10.1186/1472-6750-9-69 |