Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane(1)

BACKGROUND: The discovery of a "serrated neoplasia pathway" has highlighted the role of hyperplastic lesions of the colon as the significant precursor of colorectal adenocarcinoma. In mice, hyperplasia of the colonic mucosa is a regular phenomenon after a challenge with colonic carcinogens...

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Detalles Bibliográficos
Autores principales: Torlakovic, Emina Emilia, Keeler, Vicki, Wang, Chang, Lim, Hyun J, Lining, Leslie Ann, Laferté, Suzanne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724547/
https://www.ncbi.nlm.nih.gov/pubmed/19627619
http://dx.doi.org/10.1186/1471-2407-9-251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724547/
https://www.ncbi.nlm.nih.gov/pubmed/19627619
http://dx.doi.org/10.1186/1471-2407-9-251

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