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A Search for Energy Minimized Sequences of Proteins

In this paper, we present numerical evidence that supports the notion of minimization in the sequence space of proteins for a target conformation. We use the conformations of the real proteins in the Protein Data Bank (PDB) and present computationally efficient methods to identify the sequences with...

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Detalles Bibliográficos
Autores principales: Jha, Anupam Nath, Ananthasuresh, G. K., Vishveshwara, Saraswathi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724685/
https://www.ncbi.nlm.nih.gov/pubmed/19690619
http://dx.doi.org/10.1371/journal.pone.0006684