The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death

Dysregulation of Akt signaling is a critical player in a broad range of diseases including cancer, diabetes and heart disease. The role of Akt signaling in brain disorders is less clear. Here we show that global ischemia in intact rats triggers expression and activation of the Akt inhibitor CTMP (Ca...

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Detalles Bibliográficos
Autores principales: Miyawaki, Takahiro, Ofengeim, Dimitry, Noh, Kyung-Min, Latuszek-Barrantes, Adrianna, Hemmings, Brian A., Follenzi, Antonia, Zukin, R. Suzanne
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724841/
https://www.ncbi.nlm.nih.gov/pubmed/19349976
http://dx.doi.org/10.1038/nn.2299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724841/
https://www.ncbi.nlm.nih.gov/pubmed/19349976
http://dx.doi.org/10.1038/nn.2299

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