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The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death
Dysregulation of Akt signaling is a critical player in a broad range of diseases including cancer, diabetes and heart disease. The role of Akt signaling in brain disorders is less clear. Here we show that global ischemia in intact rats triggers expression and activation of the Akt inhibitor CTMP (Ca...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724841/ https://www.ncbi.nlm.nih.gov/pubmed/19349976 http://dx.doi.org/10.1038/nn.2299 |