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Elucidating regulatory mechanisms downstream of a signaling pathway using informative experiments
Signaling cascades are triggered by environmental stimulation and propagate the signal to regulate transcription. Systematic reconstruction of the underlying regulatory mechanisms requires pathway-targeted, informative experimental data. However, practical experimental design approaches are still in...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724975/ https://www.ncbi.nlm.nih.gov/pubmed/19584836 http://dx.doi.org/10.1038/msb.2009.45 |