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A strategy for constructing aneuploid yeast strains by transient nondisjunction of a target chromosome
BACKGROUND: Most methods for constructing aneuploid yeast strains that have gained a specific chromosome rely on spontaneous failures of cell division fidelity. In Saccharomyces cerevisiae, extra chromosomes can be obtained when errors in meiosis or mitosis lead to nondisjunction, or when nuclear br...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725114/ https://www.ncbi.nlm.nih.gov/pubmed/19594932 http://dx.doi.org/10.1186/1471-2156-10-36 |