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Gene expression profiles in mouse embryo fibroblasts lacking stathmin, a microtubule regulatory protein, reveal changes in the expression of genes contributing to cell motility

BACKGROUND: Stathmin (STMN1) protein functions to regulate assembly of the microtubule cytoskeleton by destabilizing microtubule polymers. Stathmin over-expression has been correlated with cancer stage progression, while stathmin depletion leads to death of some cancer cell lines in culture. In cont...

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Detalles Bibliográficos
Autores principales: Ringhoff, Danielle N, Cassimeris, Lynne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725145/
https://www.ncbi.nlm.nih.gov/pubmed/19643027
http://dx.doi.org/10.1186/1471-2164-10-343