Apoptosis of t(14;18)-positive lymphoma cells by a Bcl-2 interacting small molecule

Overexpression of Bcl-2 protein occurs via both t(14;18)-dependent and independent mechanisms and contributes to the survival and chemoresistance of non-Hodgkin lymphomas. HA14–1 is a nonpeptidic organic small molecule, which has been shown to inhibit the interaction of Bcl-2 with Bax, thereby inter...

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Detalles Bibliográficos
Autores principales: Abbott, David R., Abbott, Robert T., Jenson, Stephen D., Fillmore, G. Chris, Elenitoba-Johnson, Kojo S. J., Lim, Megan S.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725288/
https://www.ncbi.nlm.nih.gov/pubmed/19669197
http://dx.doi.org/10.1007/s12308-009-0028-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725288/
https://www.ncbi.nlm.nih.gov/pubmed/19669197
http://dx.doi.org/10.1007/s12308-009-0028-x

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