Dissection of the Transformation of Primary Human Hematopoietic Cells by the Oncogene NUP98-HOXA9

NUP98-HOXA9 is the prototype of a group of oncoproteins associated with acute myeloid leukemia. It consists of an N-terminal portion of NUP98 fused to the homeodomain of HOXA9 and is believed to act as an aberrant transcription factor that binds DNA through the homeodomain. Here we show that NUP98-H...

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Detalles Bibliográficos
Autores principales: Yassin, Enas R., Sarma, Nayan J., Abdul-Nabi, Anmaar M., Dombrowski, James, Han, Ye, Takeda, Akiko, Yaseen, Nabeel R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725295/
https://www.ncbi.nlm.nih.gov/pubmed/19696924
http://dx.doi.org/10.1371/journal.pone.0006719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725295/
https://www.ncbi.nlm.nih.gov/pubmed/19696924
http://dx.doi.org/10.1371/journal.pone.0006719

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