Restoration of Podocyte Structure and Improvement of Chronic Renal Disease in Transgenic Mice Overexpressing Renin

BACKGROUND: Proteinuria is a major marker of the decline of renal function and an important risk factor of coronary heart disease. Elevated proteinuria is associated to the disruption of slit-diaphragm and loss of podocyte foot processes, structural alterations that are considered irreversible. The...

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Detalles Bibliográficos
Autores principales: Huby, Anne-Cécile, Rastaldi, Maria-Pia, Caron, Kathleen, Smithies, Oliver, Dussaule, Jean-Claude, Chatziantoniou, Christos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725297/
https://www.ncbi.nlm.nih.gov/pubmed/19696925
http://dx.doi.org/10.1371/journal.pone.0006721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725297/
https://www.ncbi.nlm.nih.gov/pubmed/19696925
http://dx.doi.org/10.1371/journal.pone.0006721

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