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Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastim schedules in a chemotherapy mouse model

OBJECTIVES: Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is widely used to treat neutropenia during cytotoxic chemotherapy. The optimal scheduling of rhG-CSF is unknown and can hardly be tested in clinical studies due to numerous therapy parameters affecting outcome (chemotherap...

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Detalles Bibliográficos
Autores principales: Scholz, Markus, Ackermann, Manuela, Emmrich, Frank, Loeffler, Markus, Kamprad, Manja
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726061/
https://www.ncbi.nlm.nih.gov/pubmed/19707393