A class of DNA-binding peptides from wheat bud causes growth inhibition, G(2 )cell cycle arrest and apoptosis induction in HeLa cells

BACKGROUND: Deproteinized DNA from eukaryotic and prokaryotic cells still contains a low-molecular weight peptidic fraction which can be dissociated by alkalinization of the medium. This fraction inhibits RNA transcription and tumor cell growth. Removal from DNA of normal cells causes amplification...

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Detalles Bibliográficos
Autores principales: Mancinelli, Loretta, De Angelis, Paula M, Annulli, Lucia, Padovini, Valentina, Elgjo, Kjell, Gianfranceschi, Gian Luigi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726120/
https://www.ncbi.nlm.nih.gov/pubmed/19646247
http://dx.doi.org/10.1186/1476-4598-8-55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726120/
https://www.ncbi.nlm.nih.gov/pubmed/19646247
http://dx.doi.org/10.1186/1476-4598-8-55

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