OPA1-related dominant optic atrophy is not strongly influenced by mitochondrial DNA background

BACKGROUND: Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are the most frequent forms of hereditary optic neuropathies. LHON is associated with mitochondrial DNA (mtDNA) mutations whereas ADOA is mainly due to mutations in the OPA1 gene that encodes a mi...

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Detalles Bibliográficos
Autores principales: Pierron, Denis, Ferré, Marc, Rocher, Christophe, Chevrollier, Arnaud, Murail, Pascal, Thoraval, Didier, Amati-Bonneau, Patrizia, Reynier, Pascal, Letellier, Thierry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726129/
https://www.ncbi.nlm.nih.gov/pubmed/19619285
http://dx.doi.org/10.1186/1471-2350-10-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726129/
https://www.ncbi.nlm.nih.gov/pubmed/19619285
http://dx.doi.org/10.1186/1471-2350-10-70

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