Inhibitory Effects of Omacetaxine on Leukemic Stem Cells and BCR-ABL-Induced Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia in Mice

Omacetaxine mepesuccinate (formerly homoharringtonine) is a molecule with a mechanism of action that is different from tyrosine kinase inhibitors and its activity in chronic myeloid leukemia (CML) seems to be independent of BCR-ABL mutation status. Using BCR-ABL-expressing myelogenous and lymphoid c...

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Detalles Bibliográficos
Autores principales: Chen, Yaoyu, Hu, Yiguo, Michaels, Shawnya, Segal, David, Brown, Dennis, Li, Shaoguang
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726272/
https://www.ncbi.nlm.nih.gov/pubmed/19322212
http://dx.doi.org/10.1038/leu.2009.52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726272/
https://www.ncbi.nlm.nih.gov/pubmed/19322212
http://dx.doi.org/10.1038/leu.2009.52

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